Got Start | Programs | Spybot | Spybot Advanced Click Immunize At the bottom of that page, you should find Recommended miscellaneous Protections You will probably find that Lock IE Start page against User Changes is checked, uncheck it,
Now try to change your home page
Once you have satisfactorily changed your home page, put the check mark back in and close Spybot
Of all the Things I've lost, I miss my mind the most