I assume it's the FileHippo Update Checker which is trying to run.
You will have opted to run it at Startup during installation.
It's not required to start, so rather than trying to stop Vista from blocking Filehippo Updater, go to
msconfig and stop it from starting.
Look here -->>
How to use MSCONFIG in Windows Vista <<--
Have a look for an entry called <font color="blue">UpdateChecker</font> and un-check it.
It now won't run at Startup.