To build a site with no knowledge of HTML, buy Frontpage 2003 or Expression Web (slightly more involving to Frontpage)

A good web host would be www.1and1.co.uk.

If you intend to sell e-goods I recommend you use Paypal or WorldPay to handle payments.

If you wish to send the goods securely after payment, try DLGuard which integrates to both Paypal and WorldPay.

For a software installer I would Install Creator.
To create updates I would use Patch Maker.

To market your product and achieve instant Search Engine presence, use Google Adwords.

To create revenue for your site, try Google Adsense

Also ensure your site has been reviewed by Site Advisor.